• Aggressive Brain Cancer Driven By Two Collaborating Genes, Study

    Updated: 2009-12-31 17:17:55
    Story Summary: These are the findings of a study published in the 23 December advanced online issue of the journal Nature, that was led by Dr Antonio Iavarone, associate professor of neurology in the Herbert Irving Comprehensive Cancer Center, and Dr Andrea Califano, director of the Columbia Initiative in Systems Biology, both at Columbia University [...] Related posts:Columbia scientists discover 2 genes that drive aggressive brain cancersGene vital to brains stem cells implicated in deadly brain cancerGenes linked to aggressive childhood brain tumours found

  • Natural Flu-Fighting Protein In Human Cells Discovered By Scientists

    Updated: 2009-12-31 15:02:33
    Story Summary: In experiments in human and mouse cells, the flu-fighting proteins prevented or slowed most virus particles from infecting cells at the earliest stage in the virus lifecycle. The anti-viral action happens sometime after the virus attaches itself to the cell and before it delivers its pathogenic cargo. When we knocked the proteins out, [...] Related posts:Scientists discover natural flu-fighting protein in human cellsNatural flu-fighting protein discovered in human cellsResearchers Find Human Protein that Prevents H1N1 Influenza Infection

  • Disinfectants may promote growth of superbugs

    Updated: 2009-12-31 14:23:04
    Story Summary: The findings could have important implications for how the spread of infection is managed in hospital settings. Researchers from the National University of Ireland in Galway found that by adding increasing amounts of disinfectantto laboratory cultures of Pseudomonas aeruginosa, the bacteriacould adapt to survive not only the disinfectantbut also ciprofloxacin – a commonly-prescribed [...] Related posts:Test helps in fight against lung infections and for treating other life-threatening infectionsEnhanced stem cells promote tissue regenerationVirus Enzymes Could Promote Human, Animal Health

  • Scripps research team develops technique to determine ethnic origin of stem cell lines

    Updated: 2009-12-31 04:46:33
    Story Summary: Everyone who works with stem cells should be doing this kind of analysis. Greater diversity in cell samples would set the stage for more broadly relevant research by labs in academia and industry, more robust results on the safety and efficacy of potential therapies, and more successful tissue transplants. Pluripotent stem cells would [...] Related posts:2 lines account for most human embryonic stem cell research, Stanford scholar findsTwo Lines Account for Most Human Embryonic Stem Cell Research, Stanford Scholar FindsU-M study reveals lack of diversity in embryonic stem cell lines

  • Notching up a role in the multisystem disease tuberous sclerosis complex

    Updated: 2009-12-31 04:43:26
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags chinese academy independent teams medicine mutations proteins Notching up a role in the multisystem disease tuberous sclerosis complex Posted on 31 December 2009 04:43 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Notching up a role in the multisystem disease tuberous sclerosis complexDecember 28, 2009 Two independent teams of researchers have identified a role for enhanced activation of the signaling protein Notch in tumors characterized by inactivation of either the TSC1 or the TSC2 protein . As indicated by Warren Pear , at the University of Pennsylvania , Philadelphia , in an accompanying commentary , these data provide a rationale for testing whether Notch inhibitors are of benefit to those with TSC-associated tumors . Tuberous sclerosis complex TSC is a multisystem disease characterized by the formation of benign tumors in multiple organs . Results presented in the second study , by Hongbing Zhang and colleagues , at the Chinese Academy of Medical Sciences and Peking Union Medical College , Peoples Republic of China , provide

  • Scientists At The Genome Institute Of Singapore And 26 Institutes In China Identify Leprosy Genes

    Updated: 2009-12-31 01:10:28
    Story Summary: This study represents one of the largest and best organized studies of the host genetics in infectious diseases published, said Prof Edison Liu, Executive Director at the GIS. The strength of Chinese clinical sciences and of Singapores targeted genomic capabilities makes a powerful scientific combination. The key to this collaboration and one that [...] Related posts:Leprosy susceptibility genes reportedGenome Institute of Singapore and Roche NimbleGen develop rapid approach to identify H1N1 virus mutations and resistance to drugs – insciencesScientists identify cholesterol-regulating genes

  • New research could advance research field critical to personalized medicine

    Updated: 2009-12-30 23:38:33
    Story Summary: With a new chip called DMET, as many as 170 genes can be examined for more than a thousand variations. Such a development is particularly critical for cancer research, both in terms of drug discovery and treatment. Genetic variability among patients in cancer clinical trials is not commonly taken into account, a factor [...] Related posts:Goal of Personalized Medicine for Cancer Goes MainstreamGoal of Personalized Medicine for Cancer Goes MainstreamGoal of Personalized Medicine for Cancer Goes Mainstream

  • New RNA interference technique can silence up to 5 genes

    Updated: 2009-12-30 22:23:04
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags building machinery capability clinical trials corticosteroid triamcinolone diabetic retinopathy New RNA interference technique can silence up to 5 genes Posted on 30 December 2009 22:23 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Since the 1998 discovery of RNA interference the naturally occurring phenomenon in which the flow of genetic informationfrom a cells nucleusto the protein-building machinery of the cell is disrupted scientists have been pursuing the tantalizing ability to shut off any gene in the body . Specifically , they have been trying to silence malfunctioning genes that cause diseases such as cancer . How they did it : The team at MIT , along with Alnylam researchers , have developed methods to rapidly produce , assemble and screen a variety of different lipidoids , allowing them to pick out the most effective ones . The team focused on one that appeared the most promising , dubbed C12-200. If the same dosing were translated to humans , a potential therapy would only require an injection of less than 1 milliliter to

  • U-M study reveals surprising lack of genetic diversity in the most widely used human embryonic stem cell lines

    Updated: 2009-12-30 18:30:33
    Story Summary: Embryonic stem cell research has the potential to change the future of medicine, said Sean Morrison, director of the U-M Center for Stem Cell Biology and one of the study leaders. For the study, Morrison teamed up with two colleagues at the U-M Life Sciences Institute: stem cell scientist Jack Mosher and population [...] Related posts:U-M study reveals lack of diversity in embryonic stem cell linesTwo Lines Account for Most Human Embryonic Stem Cell Research, Stanford Scholar Finds2 lines account for most human embryonic stem cell research, Stanford scholar finds

  • Molecular chaperone keeps bacterial proteins from slow-dancing to destruction

    Updated: 2009-12-30 14:23:04
    Story Summary: Molecular chaperone keeps bacterial proteins from slow-dancing to destructionDecember 28, 2009 Just like teenagers at a prom, proteins are tended by chaperones whose job it is to prevent unwanted interactions among immature clients. And at the molecular level, just as at the high school gym level, its a job that usually requires a [...] Related posts:The Hindu News Update ServiceBBS proteins shown to run an export business that protects ciliaResearchers identify mechanism that helps bacteria avoid destruction in cells

  • Genomic toggle switches divide autoimmune diseases into distinct clusters

    Updated: 2009-12-30 09:52:38
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags autoimmune disease colleagues human genome molecules supervision Genomic toggle switches divide autoimmune diseases into distinct clusters Posted on 30 December 2009 09:52 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Butte , who is the studys senior author , and his colleagues looked at data from several large genome-wide association studies of single-nucleotide polymorphisms , or SNPs : tiny genomic variations that constitute the genetic underpinning for inter-individual human differences from eye color to nose shape to personality quirks . But at about one or two out of every 1,000 positions , the first persons genome may boast one variety of chemical unit , while the seconds hosts another type . There are several million SNPs in the human genome , making for a gigantic number of possible different versions of a human being , said the studys lead author , Marina Sirota , a fourth-year PhD student under Buttes supervision in Stanfords Biomedical Informatics Program . In the past few years the industrial-scale characterization of SNPs

  • Alzheimers Disease: Amyloid Precursor Protein — Good, Bad Or Both?

    Updated: 2009-12-30 08:09:26
    Story Summary: It is released when APP, a larger protein, is cut by several enzymes. Thus, Abeta and APP are involved in the early process of AD development. APP is also known to be present at the synapses between neurons though its molecular action is not understood. Synapse loss is thought to be one of [...] Related posts:New mechanism for amyloid beta proteins toxic impact on the Alzheimers brainDietary composition modulates brain mass and amyloid beta levels in a mouse model of aggressive Alzheimers amyloid pathologyAPP — Good, bad or both?

  • Sinovac Files Clinical Trial Application with SFDA for Vaccine Against Hand, Foot, and Mouth Disease

    Updated: 2009-12-30 06:23:04
    Story Summary: HFMD is common among infants and children, as most of the recently reported cases have occurred in children. Sinovac is independently developing the EV 71 vaccine and will retain full commercialization rights of the vaccine upon approval. Created by Sydney University, the animal model showed cross protection and demonstrated that the vaccine is [...] Related posts:Health Ministry: Hand-foot-mouth disease claims 50 lives this year_English_XinhuaSinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing CapabilitiesSinovac Receives Chinas First Influenza A (H1N1) Vaccine Order

  • Molecular anchor links the 2 inheritable diseases Fanconi anemia and Blooms syndrome

    Updated: 2009-12-29 19:28:38
    Story Summary: Molecular anchor links the 2 inheritable diseases Fanconi anemia and Blooms syndromeDecember 24, 2009 A new study establishes a molecular link that bridges two rare inherited disorders and explains why these diseases result in genetic instability. The research, published by Cell Press in the December 24th issue of the journal Molecular Cell, may [...] Related posts:Replication at DNA damage sites highlights Fanconi anemia and breast cancer proteinsUniversity of Florida News – UF research helps uncover potential treatment for chronic anemiaThink zinc: Molecular sensor could reveal zincs role in diseases

  • Global Hepatitis B Vaccines market analysis and forecast

    Updated: 2009-12-29 18:31:49
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags business strategies investments maximum opportunities peptcell sensitive manner Global Hepatitis B Vaccines market analysis and forecast Posted on 29 December 2009 18:31 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary com added a new report on Hepatitis B Vaccines Pipeline Analysis and Market Forecasts to 2015 which gives current and future market competition in the global hepatitis B vaccines market . Hepatitis B Vaccines Pipeline Analysis and Market Forecasts to 2015This is an essential source of information and analysis on the global hepatitis B vaccines market . Geographic markets covered in this report include the US , the UK , Italy , Spain , Germany , France , and Japan . Pipeline analysis data providing a split across different vaccine classes . Key market players covered are GlaxoSmithKline , Merck , Dynavax Technologies , Pfizer , Emergent Biosoloutions , PepTcell and Celldex Therapeutics . Each trend is independently researched to provide qualitative analysis of its implications . Key topics covered include strategic competitor

  • Genetic Causes For Disturbances In Lipid Metabolism

    Updated: 2009-12-29 14:23:04
    Story Summary: The results of our study bring us a decisive step closer in our search for markers for the early detection and therapy of serious metabolic diseases such as diabetes, Professor Suhre explained. As first step, the research team determined the concentrations of 163 metabolic products in blood samples of 1,800 participants of the [...] Related posts:OBBeC.com: Researchers Find Genetic Markers to Help Fight DiabetesRole of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic miceSchizophrenia And Bipolar Disorder Share Genetic Roots

  • Flowering powers genetic understanding

    Updated: 2009-12-29 13:10:28
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags arabidopsis messenger rna negative comments reproductive phase target Flowering powers genetic understanding Posted on 29 December 2009 13:10 by Alfie VN:F 1.6.9_936 please wait . Rating : 1.0 5 1 vote cast Story : Summary Until relatively recently genome sequencing projects , and studies of gene expression have mostly focussed on the messenger RNA transcripts produced from genes that contain the code needed to make proteins . But as well as this coding RNA , it is now becoming apparent that there are extensive amounts of non-coding RNA that has important roles in regulating gene expression . Turning off this gene triggers the plants flowering and reproductive phase , and the timing of this is crucial to the plants reproductive success . Once it has been turned off , or silenced , the gene retains the memory of this for the rest of its life and remains silenced even after the cold stimulus has been removed . Prof Dean has also discovered conserved RNA processing factors specifically process the non-coding anti-sense transcripts of FLC . This processing triggers changes in

  • Nationwide Childrens Hospital Selected as Biospecimen Core Resource for The Cancer Genome Atlas

    Updated: 2009-12-28 18:31:49
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags atlas economy grants north america pathologic specimens Nationwide Childrens Hospital Selected as Biospecimen Core Resource for The Cancer Genome Atlas Posted on 28 December 2009 18:31 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary 5 million contract from the National Cancer Institute NCI to serve as a Biospecimen Core Resource BCR for The Cancer Genome Atlas TCGA a program co-managed by the NCI and the National Human Genome Research Institute NHGRI both part of the National Institutes of Health NIH Following a three-year pilot phase , TCGA is moving forward to create a comprehensive catalog of the genomic changes involved in more than 20 common types of cancer . gov . As a BCR for TCGA , The Research Institute at Nationwide Childrens Hospital will be central to the process of acquiring both tumor and normal tissue samples and their accompanying clinical information from contributing medical and research centers . Dr . Qualman pioneered tissue banking at Nationwide Childrens with the foresight to know that linking clinical information to

  • Stanford scientists identify protein that keeps stem cells poised for action

    Updated: 2009-12-28 17:46:15
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags anticipation cells differentiation medicine proteins Stanford scientists identify protein that keeps stem cells poised for action Posted on 28 December 2009 17:46 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Stanford scientists identify protein that keeps stem cells poised for actionLike a child awaiting the arrival of Christmas , embryonic stem cells exist in a state of permanent anticipation . They must balance the ability to quickly become more specialized cell types with the cellular chaos that could occur should they act too early stop shaking those presents , kids Researchers at the Stanford University School of Medicine have now identified a critical component , called Jarid2, of this delicate balancing act one that both recruits other regulatory proteins to genes important in differentiation and also modulates their activity to keep them in a state of ongoing readiness . PRCs keep genes quiet by modifying DNA packaging proteins called histones . PRC2 is necessary to regulate the expression of developmentally important genes in

  • Genomic Differences Identified In Common Skin Diseases

    Updated: 2009-12-28 14:40:38
    Story Summary: The researchers say that the ability to distinguish between the disorders genetic and immunological signatures opens the door for more narrowly targeted therapies sorely needed by the millions of people afflicted worldwide. The scientists confirmed previously recognized immunological distinctions, but they found even more remarkable differences in the expression of genes that control [...] Related posts:Embryonic stem cells, reprogrammed skin cells have inherent differencesEmbryonic stem cells, reprogrammed skin cells have inherent differencesEmbryonic stem cells, reprogrammed skin cells have inherent differences

  • Mobilizing the repair squad: Critical protein helps mend damaged DNA

    Updated: 2009-12-28 07:29:15
    Story Summary: Yet precisely how the initial damage signal is converted into a repair response remains unclear. Researchers at the Salk Institute for Biological Studies have now solved a crucial piece of the complex puzzle. The DNA in our cells is under constant attack from reactive chemicals generated as byproducts of cellular metabolism. In yeast, [...] Related posts:Protein Complex Key in Avoiding DNA Repair Mistakes, CancerBRIT1 allows DNA repair teams access to damaged sitesSingle-stranded DNA-binding protein is dynamic, critical to DNA repair

  • Childrens Hospital Tops Lists of Medical Advances in 2009

    Updated: 2009-12-28 06:31:49
    Story Summary: Our researchers and physicians are pushing the boundaries of biomedical knowledge, and advancing care for children worldwide, said Philip R. Johnson, M. D. , chief scientific officer at The Childrens Hospital of Philadelphia. We are proud to see some of these exciting accomplishments recognized in a broad public forum. Six of the [...] Related posts:More Gene Mutations Linked To Autism RiskMore Gene Mutations Linked To Autism RiskThe Childrens Hospital of Philadelphia :: Gene Findings Unlocking Reasons for Neuroblastoma Risk

  • $14.6 Million To Expand Pathogen Database, Expedite Worldwide Research Awarded To Penn, Georgia Collaboration

    Updated: 2009-12-28 00:16:38
    , , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags collaboration factual information protein expression proteins thousand dollars 14.6 Million To Expand Pathogen Database , Expedite Worldwide Research Awarded To Penn , Georgia Collaboration Posted on 28 December 2009 00:16 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary EuPathDB has been expanded several times based on its success in expediting infectious disease research . Toxoplasma and Neospora caninum are also economically important as sources of congenital infection in farm animals . The parasites responsible for kala azar Leishmania African sleeping sickness Trypanosoma brucei and Chagas disease Trypanosoma cruzi which have been incorporated into this resource with support from the Bill Melinda Gates Foundation . The EuPathDB database is one of four Pathogen Bioinformatics Resource Centers supported by the NIH and is directed by principal investigator David S . Roos , E . Otis Kendall Professor of Biology in the School of Arts and Sciences at the University of Pennsylvania . Co-investigators include Christian Stoeckert of the

  • Citrus surprise: Vitamin C boosts the reprogramming of adult cells into stem cells

    Updated: 2009-12-27 21:12:15
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags adult cells antioxidants stem cell surprise vitamin c Citrus surprise : Vitamin C boosts the reprogramming of adult cells into stem cells Posted on 27 December 2009 21:12 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Now , a study published online on December 24th by Cell Press in the journal Cell Stem Cell uncovers an unexpected new role for this natural compound : facilitating the generation of embryonic-like stem cells from adult cells . Over the past few years , we have learned that adult cells can be reprogrammed into cells with characteristics similar to embryonic stem cells by turning on a select set of genes . They became particularly interested in antioxidants , hypothesizing that they might suppress ROS and cell senescence , which seems to be a major roadblock for the generation of iPSCs . Somewhat to their surprise , they found that other antioxidants do not have the same effect , but vitamin C does seem to act at least in part through slowing cell senescence Read the Full Story VN:F 1.6.9_936 Rating : 0 from 0 votes

  • FDA Licenses New Influenza Vaccine Designed Specifically for People 65 Years of Age and Older

    Updated: 2009-12-27 16:56:54
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags fda licenses obligation operations products phase iii risk factors FDA Licenses New Influenza Vaccine Designed Specifically for People 65 Years of Age and Older Posted on 27 December 2009 16:56 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Fluzone High-Dose vaccine was specifically designed to generate a more robust immune response in people 65 years of age and older . However , as people age , research has shown that the immune system weakens . Older adults are not only more susceptible to infections , but also less responsive to vaccination . When infected with the influenza virus , they are less able to mount an effective immune response to neutralize the attack . About Fluzone High-Dose Vaccine Fluzone High-Dose vaccine is an inactivated influenza virus vaccine indicated for active immunization of people 65 years of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine . This indication is based on the immune response elicited by Fluzone High-Dose vaccine and there have been

  • Small changes in protein chemistry play large role in Huntingtons disease

    Updated: 2009-12-27 10:55:15
    Story Summary: Recent studies have demonstrated that a small region adjacent to the mutated segment plays a major role in the toxicity. Two new studies supported by the National Institutes of Health show that very slight changes to this region can eliminate signs of Huntingtons disease in mice. Huntingtons disease is inherited, and usually strikes [...] Related posts:Subtle change dramatically reduces pathogenic potential of Huntingtons proteinUCLA scientists find molecular switch to prevent Huntingtons disease in miceHuntingtons Protein May Have A Crony / Science News

  • A novel gene found for childhood-onset asthma

    Updated: 2009-12-27 10:24:54
    Story Summary: Because the gene, called DENND1B, affects cells and signaling molecules thought to be instrumental in the immune system overreaction that occurs in asthma, the discovery may have singled out an important target for new treatments. It also is highly heterogeneous, manifesting differently in different patients, and appears to operate differently in childhood-onset asthma [...] Related posts:Novel genetic region identified for childhood asthma in MexicansGene Variant Seems to Guard Against Asthma, COPDasthma : Scientists unearth the yin and yang of asthma | Entertainment and Showbiz!

  • Seven Johns Hopkins Researchers Named AAAS Fellows-12/17/09

    Updated: 2009-12-27 00:38:15
    Story Summary: This years AAAS Fellows will be announced in the AAAS News & Notes section of the journal Scienceon Dec. 18. New fellows will be presented with an official certificate and a gold and blue (representing science and engineering, respectively) rosette pin on Saturday, Feb. 20, during the 2010 AAAS Annual Meeting [...] Related posts:Five Johns Hopkins University Researchers Named 2008 AAAS Fellows- 12/18/08Five Johns Hopkins University Researchers Named 2008 AAAS Fellows- 12/18/08M. Elizabeth Halloran named AAAS Fellow

  • Synergistic interaction enhances pathogenesis of Parkinsons disease

    Updated: 2009-12-26 21:20:54
    Story Summary: The research, published by Cell Press in the December 24 issue of the journal Neuron,identifies a new potential therapeutic option for preventing PD-associated neuropathology. Mutations in the ?-synuclein (?-syn) and Leucine-rich repeat kinase (LRRK2) genes have been linked with inherited and sporadic forms of PD and previous research has shown that accumulation of [...] Related posts:Enzyme Fights Mutated Protein In Inherited Parkinsons DiseaseEnzyme Fights Mutated Protein In Inherited Parkinsons DiseaseNews Items: MUHC researcher awarded $500,000 to study pathogenesis of infectious disease

  • Subtle change dramatically reduces pathogenic potential of Huntingtons protein

    Updated: 2009-12-26 14:48:54
    Story Summary: Recent work has revealed that two specific amino acids in htt, serine 13 (S13) and serine 16 (S16), can be phosphorylated. Specifically, they replaced the S13 and S16 with phosphomimetic aspartate (SD) or phosphoresistant alanine (SA). The researchers found that full-length mhtt induced motor and psychiatric-like behavioral deficits, mhtt aggregation, and selective neurodegeneration [...] Related posts:Researchers Find Potential Treatment for Huntingtons DiseaseSmall changes in protein chemistry play large role in Huntingtons diseaseMolecular 2-Step Leading To Protein Clumps Of Huntingtons Disease Described By Pitt Researchers

  • One Step Closer to Closure-12/23/09

    Updated: 2009-12-26 14:21:15
    Story Summary: In the Dec. 6 issue of Nature Cell Biology,researchers from the Johns Hopkins University School of Medicine team with colleagues at the University of California, Berkeley to report a never-before known link between protein transport and mouse spinal cord development, a discovery that opens new doors for research on all spinal defects. [...] Related posts:A Step Closer To Understanding Skin, Breast And Other Cancersglobeandmail.com: Folic acid may raise cancer risk in offspringH1N1 flu vaccine a step closer as firms test seed | Reuters

  • Seeing how evolutionary mechanisms yield biological diversity

    Updated: 2009-12-26 13:29:25
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags biological diversity cichlid fishes key role lake victoria little understanding Seeing how evolutionary mechanisms yield biological diversity Posted on 26 December 2009 13:29 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary In research published in the December 21, 2009 issue of the journal PLoS Biology , Assistant Professor Karen Carleton , together with post-doctoral associate Chris Hofmann and graduate student Kelly OQuin , in the University of Maryland Department of Biology , and collaborators Justin Marshall , University of Queensland Tom Cronin , University of Maryland , Baltimore County UMBC and Ole Seehausen , University of Bern describe how over 60 species of cichlid fish from Lake Malawi and Lake Victoria have adapted their visual sensitivity in response to specific ecological factors , including what they eat and the clarity of the water in which they swim . Evolutionary biologists seek to understand the mechanisms behind genetic changes that have led to the vast diversity of life on Earth . Yet there has been little

  • Researchers find new patterns in H1N1 deaths

    Updated: 2009-12-26 09:42:25
    Story Summary: The lack of information on the pathophysiology of this novel disease is a limitation that prevents better clinical management and hinders the development of a therapeutic strategy, said lead author, Thais Mauad, M. D. , Ph. D. , associate professor of the Department of Pathology at Sao Paulo University, in Brazil. All presented [...] Related posts:Cytokine Storm may be Cause of Swine Flu Pneumonia, Deaths, Flu and ColdOfficialWire: H1N1 Flu May Induce A Cytokine StormResearchers Find Human Protein that Prevents H1N1 Influenza Infection

  • UCSB scientists discover how the brain encodes memories at a cellular level

    Updated: 2009-12-26 08:16:54
    Story Summary: The finding, published in the December 24 issue of the journal Neuron,could eventually lead to the development of new drugs to aid memory. The team of scientists is the first to uncover a central process in encoding memories that occurs at the level of the synapse, where neurons connect with each other. Those [...] Related posts:Investigating a proteins role in brain linksJohns Hopkins Neuroscientists Watch Memories Form in Real Time- 6/10/09Investigating a sometimes-faulty proteins role in brain links – MIT News Office

  • UCLA scientists find molecular switch to prevent Huntingtons disease in mice

    Updated: 2009-12-26 04:04:15
    Story Summary: Published in the Dec. 24 edition of the journal Neuron, the discovery suggests a new approach to treating the genetic disorder, which ultimately leads to death in as little as 10 years. Affecting one out of every 10,000 Americans, Huntingtons progressively deprives patients of their ability to walk, speak, think clearly and [...] Related posts:Small changes in protein chemistry play large role in Huntingtons diseaseCaltech researchers show efficacy of gene therapy in mouse models of Huntingtons diseaseMolecular 2-Step Leading To Protein Clumps Of Huntingtons Disease Described By Pitt Researchers

  • Columbia scientists discover 2 genes that drive aggressive brain cancers

    Updated: 2009-12-26 01:44:54
    Story Summary: Before this study, cancer researchers had little idea why glioblastoma is so aggressive. The two genes are active in about 60 percent of all glioblastoma patients and help identify poor-prognosis patients. All patients in the study whose tumors showed activation of both factors died within 140 weeks after diagnosis, while one half of [...] Related posts:Genes linked to aggressive childhood brain tumours foundGenes Found To Play Role In Breast Cancers Spread To BrainIndian Scientists Discover Gene Behind Brain Disorder

  • 2010 preview: Genome sequencing for all

    Updated: 2009-12-25 22:21:25
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags cambridge massachusetts genome genomes health nucleotide 2010 preview : Genome sequencing for all Posted on 25 December 2009 22:21 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary A rival outfit , Knomein Cambridge , Massachusetts , says it will sequence entire genomes for 12,000. If you cant wait , you can go for a quick scan of the million or so common spelling mistakes in the genome though these single nucleotide polymorphisms dont come close to encompassing the vast array of mutations that influence our health . Even having your complete genome wouldnt leave you much the wiser for now . But give geneticists a few years to pore over thousands of full sequences , and we probably will . I dont think that will be a problem since the issues you listed(except race , one has to wonder why you think that is a contentious issue are at least in part caused by environment . And who knows how many computer data errors will cause serious concern or misdiagnosis . If you think a particular comment breaks these rules then please use the Report link

  • Opening new frontiers: First volume of microbial encyclopedia published

    Updated: 2009-12-25 19:12:54
    Story Summary: From the tree of microbial diversity the genomes from only a few branches have been sequenced. What distinguishes GEBA is that it is less about the individual genomes and more about building a more balanced catalog of the diversity of genomes present on the planet which in turn should facilitate searches for novel [...] Related posts:Encyclopedia of microbe genomes: Chapter 1Reviews Of Microbial Gene Language Published In Special Issue Of Trends In MicrobiologyReviews of microbial gene language published in special issue of Trends in Microbiology

  • Genocea Eyes Vaccines that Treat, Not Just Prevent, Infectious Diseases

    Updated: 2009-12-25 18:34:25
    Story Summary: Genocea (pronounced Jen-O-shuh) has been one of the biotech startups to watch in town since it raised $23 million in its Series A venture round in February; I profiled the company and its CEO Staph Bakali back in August. An estimated 45 million peoplein the U. S. ages 12 and older have [...] Related posts:Genocea Biosciences Expands Scientific Advisory Board with Appointment of Four Vaccine ExpertsURI awarded $13 million grant to develop vaccines for emerging infectious diseasesValue of vaccination in fight against diseases

  • Huntingtons Disease: IKK May Act As Both Inhibitor And Promoter

    Updated: 2009-12-25 14:47:25
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags brain disorder health care medical advice medical information proteasome Huntingtons Disease : IKK May Act As Both Inhibitor And Promoter Posted on 25 December 2009 14:47 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Compared to wild type , mutant Htt with an expanded polyglutamine stretch was degraded inefficiently , but a version that mimicked IKK phosphorylation with negatively charged aspartate residues was still less toxic to neuronal slice cultures . The latter pathway would predominate in older patients because proteasome and lysosome function declines with age . Therapies aimed at IKK might need to either enhance or block the kinases function , depending on the patients age and stage of disease . Source : Rita Sullivan Rockefeller University Press Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional . What Causes Huntingtons Disease 02 Aug 2009Huntingtons disease is an incurable ,

  • Gene Therapy Makes Mice Breath Easier

    Updated: 2009-12-25 11:00:25
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags emphysema factual information inhaled corticosteroids medicine persistent asthma Gene Therapy Makes Mice Breath Easier Posted on 25 December 2009 11:00 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary TITLE : Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages AUTHOR : Darrell N . Kotton , Boston University School of Medicine , Boston , Massachusetts , USA . Contact Our News EditorsFor any corrections of factual information , or to contact the editors please use our feedback form . Please send any medical news or health news press releases to : These are the most read articles from this news category for the last 6 months : What Is Bronchitis What Causes Bronchitis 10 Nov 2009The bronchial tubes , or bronchi , connect the windpipe to the lungs . Asthma in Kids Under 5Up to 10 of children in the United States have asthma , and asthma control is key to preventing long-term problems . National treatment guidelines recommend inhaled corticosteroids to control symptoms in very young

  • Blog – How Sun and Smoke Trigger Cancer

    Updated: 2009-12-25 09:24:17
    Story Summary: We can also see the desperate attempts of our genome to defend itself against the damage wreaked by the chemicals in cigarette smoke or the damage from ultraviolet radiation. The DNA sequence of the cancer cells also revealed that the cells had attempted to repair their smoke-damaged DNA using two mechanisms, but the [...] Related posts:Cancer genomes reveal risks of sun and smokeGenetic Changes Outside Nuclear DNA Suspected to Trigger More than … – Newswise (press release)Scientists use DNA sequencing to attack lung cancer

  • Gene therapy makes mice breath easier: Preventing progression of emphysema

    Updated: 2009-12-25 07:13:25
    Story Summary: The study, which appears on-line in the Journal of Clinical Investigation, describes a method to express therapeutic genes in lung tissue for a lifetime after only a single treatment. Alpha-1 Anti-trypsin Deficiency is the most common inherited form of emphysema seen in young people due to a mutation in the Alpha-1 Anti-trypsin gene. [...] Related posts:Gene Therapy Makes Mice Breath EasierGene variant may help against emphysema, asthmaGene Therapy Trial Succeeds In Spurring Production Of A Protective Protein

  • Encyclopedia of microbe genomes: Chapter 1

    Updated: 2009-12-25 06:08:54
    Story Summary: Unlike eukaryotic organisms such as people, yeast and oak trees, the cells of prokaryotes have no membrane wrapped around their DNA. Thats like making a map of the world and only mapping three cities, Eisen said. The new study, called the Genomic Encyclopedia of Bacteria and Archaea or GEBA, looks instead at representatives [...] Related posts:Opening new frontiers: First volume of microbial encyclopedia publishedYour Bug-Coated Windshield Is Lousy With GenomesThe mitochondrial and plastid genomes of Volvox carteri: bloated molecules rich in repetitive DNA. – 7thSpace Interactive

  • How Flu Succeeds

    Updated: 2009-12-25 05:59:17
    Story Summary: The team also identified small molecule compounds that act on several of these factors and inhibit viral replication, pointing to new ways to treat flu. These findings were published online on December 21 in the journal Nature. As a result, there is now widespread resistance to two classes of antiviral drugs. However, by [...] Related posts:Mount Sinai leads unprecedented, NIH-supported attempt to discover rules for assembling human tissueMount Sinais Dr. Benjamin tenOever to be honored by White HouseNIH designates Salk Institute one of seven national basic research centers focused on vision

  • Genomes of identical twins reveal epigenetic changes that may play role in lupus

    Updated: 2009-12-25 03:26:25
    Story Summary: In a study published online in Genome Research, scientists have studied twins discordant for the autoimmune disease lupus, mapping DNA modifications across the genome and shedding light on epigenetic changes that may play a role in the disease. Because the genetic makeup of monozygotic twins (commonly known as identical twins) is nearly identical, [...] Related posts:Lupus not identical in twinsMisread Epigenetic Signals Play Role In Leukemia / Science NewsPR-USA.net – Genes Play a Role in Glycemic Control in People With Type 1 Diabetes

  • Lupus not identical in twins

    Updated: 2009-12-25 00:49:17
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags autoimmune disease cells genetic makeup immune system twins Lupus not identical in twins Posted on 25 December 2009 12:49 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Fewer DNA methylation marks may leave one twin vulnerable to the inflammatory autoimmune disease , even while the other sibling remains healthy , a new study appearing online December 22 in Genome Researchshows . The finding suggests that environmental factors determine whether genetically susceptible twins will contract lupus , or systemic lupus erythematosus , which is characterized by the immune system attacking the bodys own cells . Scientists have looked beyond differences in the genes of healthy people and people who get autoimmune disorders and found that people with lupus and rheumatoid arthritis have lower levels of DNA methylation than healthy people . But previous studies havent ruled out a genetic contribution for lupus , Richardson says , because the healthy controls and lupus patients in those studies didnt have exactly the same genetic makeup . He expects

  • Mystery solved: Scientists now know how smallpox kills

    Updated: 2009-12-24 23:39:25
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags faseb j immunity molecules research associations target Mystery solved : Scientists now know how smallpox kills Posted on 24 December 2009 23:39 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary These studies demonstrate the production of an interferon binding protein by variola virus and monkeypox virus , and point at this viral anti-interferon protein as a target to develop new therapeutics and protect people from smallpox and related viruses , said Antonio Alcami , Ph . In a high containment laboratory at the Centers for Disease Control and Prevention in Atlanta , scientists produced the recombinant proteins from the variola virus and a similar virus that affects monkeys , causing monkeypox . The researchers then showed that cells infected with variola and monkeypox produced a protein that blocks a wide range of human interferons , which are molecules produced by our immune systems meant to stop viral replication . The re-emergence of pox viruses has potentially devastating consequences for people worldwide , as increasing numbers of

  • Medicago reports positive Phase I results for its avian flu pandemic vaccine

    Updated: 2009-12-24 23:09:17
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags influenza vaccines manufacturing technology time frame transgenic plants u s grant Medicago reports positive Phase I results for its avian flu pandemic vaccine Posted on 24 December 2009 23:09 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary TSX-V : MDG a biotechnology company focused on developing highly effective and affordable vaccines based on proprietary manufacturing technologies and Virus-Like Particles VLPs today reported positive interim results from a Phase I human clinical trial with its H5N1 Avian Influenza vaccine candidate H5N1 vaccine The vaccine was found to be safe , well tolerated and also induced a solid immune response . It may also allow us to access new sources of non-dilutive funding available through U . S . grant programs and by organizations interested in funding the development of better technologies for pandemic vaccine production . HI titers greater than 1:40 were developed in 50 of the subjects in the 20 mcg group . The H5N1 vaccine also induced the production of antibodies cross-reacting with two other

  • Altering malignant cells structure said to possibly slow spread of cancer

    Updated: 2009-12-24 19:52:25
    Story Summary: Cells respond to signals from the environment by several ways. Among the most critical are the changes in lipids called phosphoinositides as well as in tyrosine phosphorylation, the addition of a phosphate group to specific cellular proteins. The long-term goal of our research is to define how signals that alter the cytoskeletal architecture [...] Related posts:Lung cancer suppresses miR-200 to invade and spreadTechnique Distinguishes Malignant Tumor Cells From Healthy Tissue In Real Time During SurgeryRNA snippet suppresses spread of aggressive breast cancer

  • Marijuana, Alcohol Addiction May Share Genes

    Updated: 2009-12-24 16:13:12
    Story Summary: Despite a genetic tendency, no one is predestined to abuse either substance, Sartor noted. Marijuana is the most commonly used illegal drug, according to the study, citing a 2008 survey that found about 42 percent of high school seniors reported having tried marijuana. About 5 percent said they had used it daily during [...] Related posts:Common Genetic Factors Contribute To Alcohol And Marijuana Use And DependenceTobacco, marijuana and alcohol may lower levels of some anti-HIV drugsBaltimore Science News Examiner: Russell Brand and how future addiction treatments could target genes

  • Chicago Cancer Genome Project studies genetics of 1,000 tumors

    Updated: 2009-12-24 16:05:25
    Story Summary: That process is already gaining traction at the University of Chicagos Institute for Genomics and Systems Biology (IGSB), where researchers are one year into a three-year project to collect and analyze the genetic sequence and variations of every gene expressed by 1,000 tumors. Over the past year, working closely with physicians, the IGSB [...] Related posts:UNC awarded Cancer Genome Atlas grantChicago team uses artificial intelligence to diagnose metastatic cancerQuestions surround Mexican genome project

  • Microcephaly genes associated with human brain size

    Updated: 2009-12-24 09:29:17
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags brain size collaboration patient groups proteins tuberculosis bacterium Microcephaly genes associated with human brain size Posted on 24 December 2009 09:29 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary The study , which involved collaboration between researchers from the University of Oslo , the University of California , San Diego and Scripps Translational Science Institute in La Jolla , California , will be published on line the week of December 21 in the Proceedings of the National Academy of Science . In relation to body size , brain size has expanded dramatically throughout primate and human evolution . It is obvious that such anatomical changes must have a basis in genetic alterations , said Lars M . Rimol , a research fellow at the University of Oslo . Several previous MRI studies have attempted to demonstrate a link between single polymorphisms an inherited genetic variationthat is found in more than one percent of the population in these genes and brain size in healthy human adults , all of them unsuccessful . The initial

  • Model for powerful flu fighters from existing drugs

    Updated: 2009-12-24 09:01:12
    Story Summary: Loop regions, shown in brown/gray, can twist into many more shapes than other parts of the enzyme (green and white) can. Computer compatibility tests might help flu-fighting drugs find their groove. All influenza viruses have a neuraminidase enzyme, but the protein comes in several subtypes. Drugs currently used against flu — including oseltamivir, [...] Related posts:Model assembles powerful flu fighters from existing drugsAileronas New Class of Drugs Shown to Get Inside Cells to Block Prime Cancer TargetScripps studies protein that makes cancer resist chemotherapy

  • Gene for devastating kidney disease discovered

    Updated: 2009-12-24 08:31:25
    Story Summary: The study, published online December 20 by Nature Genetics, may provide clues to developing treatments for the disease, focal segmental glomerulosclerosis (FSGS), which currently forces children and young adults onto dialysis and often requires a kidney transplant. No effective treatments are known, and years of research have failed to uncover the underlying disease [...] Related posts:Mutation In Renin Gene Linked To Inherited Kidney DiseaseNews: Mouse Model Developed to Understand T Cellsa Role in Kidney Damage Disease.Study finds novel genetic risk factors for kidney disease

  • Genetic study clarifies African and African-American ancestry

    Updated: 2009-12-24 06:04:17
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags africa cornell university human populations populations present day Genetic study clarifies African and African-American ancestry Posted on 24 December 2009 06:04 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Credit : Sarah Tishkoff and the University of PennsylvaniaPeople who identify as African-American may be as little as 1 percent West African or as much as 99 percent , just one finding of a large-scale , genome-wide study of African and African-American ancestry released today . An international research team led by scientists from the University of Pennsylvania and Cornell University has collected and analyzed genotype data from 365 African-Americans , 203 people from 12 West African populations and 400 Europeans from 42 countries to provide a genome-wide perspective of African and African-American ancestry . The team found that , while some West African populations are nearly indistinguishable , there are clear and discernible genetic differences among some groups , divided along linguistic and geographic lines . There are

  • Protein that represses genes may play role in cell growth

    Updated: 2009-12-24 02:39:17
    Story Summary: Protein that represses genes may play role in cell growthDecember 21, 2009 By Krishna Ramanujan(PhysOrg. com) — A Cornell study shows the protein not only activates some genes involved in the regulation of cell growth and signaling, but also may play a role in preventing cancers by inhibiting cell proliferation. Published in the [...] Related posts:ERKs got rhythm: Protein that controls cell growth found to cycle in and out of cell nucleusProtein That Promotes Cancer Cell Growth IdentifiedHealth – Do genes play a role in heart attacks? by Destination Sante

  • 2009 Science News of the Year: Genes & Cells

    Updated: 2009-12-24 01:49:12
    Story Summary: The protein, called p53, protects cells from becoming cancerous by sensing stress and either shutting down cell division or triggering cell death. Researchers at the University of Tokyo and colleagues have discovered that p53 also plays a role in slicing stretches of RNA into regulatory molecules called microRNAs (SN: 8/15/09, p. 8). [...] Related posts:Science News From Weill Cornel: November 2009Newswise Science News | Research Reveals How Cells Tell TimeLarge DNA Stretches, Not Single Genes, Shut Off As Cells Mature- 1/18/09

  • Adding a genetic supertool

    Updated: 2009-12-24 00:57:25
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags chemotherapy israel medicine mutations sequencer Adding a genetic supertool Posted on 24 December 2009 00:57 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Able to trace rare genetic disease mutations , the tool can turn a single laboratory into a fertile genetic research center . Now , Tel Aviv University has its own deep sequencer one of the first in Israel a Genome Analyzer housed in a new Genome Facility . Tel Aviv University will use the Genome Analyzer to rapidly advance genomic research , says Prof . Avraham . Prof . Gil Ast of the Department of Human Genetics , Sackler School of Medicine , is another of the pioneering researchers at Tel Aviv University who are using the deep sequencing tool . It will be also used by young researchers such as Dr . Noam Shomron , who will also run the facility . Using a deep sequencer tool , Dr . Shomron is working in the rapidly developing area of personalized medicine , investigating why some patients respond well to chemotherapy while others do not Read the Full Story VN:F 1.6.9_936 Rating : 1

  • FDA Grants Emergency Use Authorization for TessAraeA(r) 2009 H1N1 Influenza A Virus Assay Based on the AffymetrixA(r) GeneChipA(r) Platform

    Updated: 2009-12-24 00:54:17
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags cleveland ohio drug efficacy genetic variations microarray technology section 21e FDA Grants Emergency Use Authorization for TessAraeA(r 2009 H1N1 Influenza A Virus Assay Based on the AffymetrixA(r GeneChipA(r Platform Posted on 24 December 2009 12:54 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary aWe are very pleased that the EUA from the FDA will give healthcare providers another emergency tool for the detection of the 2009 H1N1 influenza A virus during the current outbreak using the TessArray RM-Flu test,a said Klaus SchA$ fer , MD , MPH , president and CEO of TessArae . a GeneChip technology , through the MyGeneChip Custom Array Program , enables researchers to perform large-scale resequencing with uniform sequence coverage , long read lengths to minimize curation and assembly time , high accuracy and reproducibility , and efficient data management , while reducing the overall cost per base . aThe authorization of the RM-Flu test builds on the success of our MyGeneChip Custom Program , including GeneChipA(r Resequencing Arrays for

  • Protein link may be key to new treatment for aggressive brain tumor

    Updated: 2009-12-24 00:18:25
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags brain tumor diversity jogi medicine protein link Protein link may be key to new treatment for aggressive brain tumor Posted on 24 December 2009 12:18 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Collectively , our studies indicate that TRPC6 is a key mediator of tumor growth of GBM . It promotes cell growth during development of the central nervous system . Chan and his team ran several experiments with cancerous brain tissue obtained from Florida Hospital in Orlando and Duke University Medical Center . They found that this protein is strongly expressed and functional in brain tumor cells . Malignant gliomas remain one of the most devastating cancers despite recent advancements . Others who contributed to the research include Raji Venkataraman , Daniel Barrera , Anusha Naganathan , Meenu Madan , Leena Paul , Jogi V . Pattisapu , George A . Kyriazis and Kiminobu Sugaya from UCF Sergey Bushnev from Florida Hospital Cancer Institute and Justin D . Lathia and Jeremy N . Rich from the Duke University Medical Center and the Department of

  • New, virulent strain of MRSA poses renewed antibiotic resistance concerns

    Updated: 2009-12-23 21:10:25
    Story Summary: The good news is that so far the community strain is more treatable, if we can keep it that way, he said. Although infections are usually minor, some can spread rapidly, cause pneumonia, tissue necrosis, blood infections, shock and death. In the new research based on laboratory analysis, scientists identified linezolid and moxifloxacin [...] Related posts:MRSA strain linked to high death ratesNew effort to battle antibiotic resistance rallies researchers throughout Harvard UniversityNew genes give gut bacteria antibiotic resistance

  • Compound Found To Safely Counter Deadly Bird Flu

    Updated: 2009-12-23 19:49:17
    Story Summary: Now, however, a study published this week (Dec. 21) in the Proceedings of the National Academy of Sciences (PNAS) suggests that a new compound, one on the threshold of final testing in humans, may be more potent and safer for treating bird flu than the antiviral drug best known by the trade [...] Related posts:Compound found to safely counter deadly bird fluAdapting To A New Host: Bird Flu Leaves The NestNanoViricides, Inc. Says Flu-Cide Drug Designed To Destroy All Influenza A Viruses Including Swine And Bird Flu

  • Initiation Of CYT107 Study In HBV Expands Companys Hepatitis Investigations, Which Include Three Ongoing Studies In Hepatitis C (HCV)

    Updated: 2009-12-23 16:24:17
    , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags dna virus injection drug international investigations literature search study participation Initiation Of CYT107 Study In HBV Expands Companys Hepatitis Investigations , Which Include Three Ongoing Studies In Hepatitis C HCV Posted on 23 December 2009 16:24 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary The trial will initiate at 7 study centers in France and 3 sites in Italy . Bi-therapy group : patients will receive CYT107 antiviral treatment entecavir or tenofovir and one control patient will receive antiviral treatment only . Patients with chronic HBeAg-negative hepatitis will be assessed for study participation if they have undetectable HBV DNA for at least 3 months when treated with entecavir or tenofovir . The repeated administration of GenHevac B Pasteur(R vaccine should support the production of anti-HBV specific T cells , including central memory T cells , and it is these cells that will be further augmented and supported by CYT107 treatment and,3 . The restoration of a specific immune response should translate into HBsAg

  • Major breakthrough may pave the way for therapeutic vaccines

    Updated: 2009-12-23 11:25:12
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags collaboration colleagues drugs health diseases lymphoblastic leukaemia Major breakthrough may pave the way for therapeutic vaccines Posted on 23 December 2009 11:25 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary However , there has now been a major breakthrough in this area . The cost of these protein pharmaceuticals is high , between 15 000 and 150 000 dollars per patient and year , and long periods of treatment are often needed . Therapeutic vaccines contain no pre-produced antibodies but rather stimulate our immune system to produce its own therapeutic antibodies . They are considerably less expensive to manufacture than the drugs that are now being produced . Until now , there has been only one adjuvant that is approved for use in humans , and this substance has proven to have little or no effect when the target molecule is endogenous , that is , produced by the body itself . To develop new and more potent adjuvants , researchers from Uppsala University , in collaboration with colleagues from the Shemyakin-Ovchinnikov Institute in

  • Novel Strategy Adopted By H1N1 Influenza To Enable It To Move From Birds To Humans

    Updated: 2009-12-23 09:34:17
    Story Summary: The researchers also discovered another strategy – one not yet adopted by any known flu virus – by which influenza virus can increase its virulence even more. As mechanistic biologists, we are hoping that by understanding how the virus works at the molecular level, we will be able to predict with more accuracy [...] Related posts:H1N1 influenza adopted novel strategy to move from birds to humansArbor Vita Receives FDA Clearance Of Its AVantage(TM) A/H5N1 Flu Diagnostic – First Rapid Test For Avian Influenza In HumansNew biological route for swine flu to human infections

  • TAU Researchers Unravel The Mysteries Of DNA Packaging

    Updated: 2009-12-23 06:09:17
    Story Summary: Without a talented editor, a screening would have no meaning. The RNA spools that make up DNA in our genes need careful editing, too. Their groundbreaking findings, recently published in Nature Structural and Molecular Biology, reveal a new mechanism to explain how splicing works. This can give new clues to scientists seeking to [...] Related posts:Faster, Cheaper DNA Sequencing Method Developed By Boston University ReseachersColorectal Cancer – MDC Researchers Identify Genetic Markers For Metastasis FormationVaccine Against Chlamydia Not Far Away

  • One Step Closer To Cracking The Histone Code

    Updated: 2009-12-23 02:44:17
    Story Summary: Many biologists believe the modifications on histones are a code, analogous to the genetic code. This work represents a step toward uncovering the molecular basis for how demethylases handle multiple signals on histones, says Paula Flicker, PhD, who oversees cell signaling grants at the National Institutes of Healths National Institute of General Medical [...] Related posts:Scientists take a step towards uncovering the histone codeDetermination of enriched histone modifications in non-genic portions of the human genome – 7thSpace InteractiveMisreading Of Histone Code Linked To Human Cancer

  • Faster, Cheaper DNA Sequencing Method Developed By Boston University Reseachers

    Updated: 2009-12-23 00:59:17
    Story Summary: In a study published in the Dec. 20 online edition of Nature Nanotechnology, a team led by Boston University Biomedical Engineering Associate Professor Amit Meller details pioneering work in detecting DNA molecules as they pass through silicon nanopores. The technique uses electrical fields to feed long strands of DNA through four-nanometer-wide pores, [...] Related posts:Boston University reseachers develop faster, cheaper DNA sequencing methodResearchers Develop Faster And Cheaper Way To Find Disease GenesTAU Researchers Unravel The Mysteries Of DNA Packaging

  • Transgenomic, Inc. Executes License Option agreement for Parkinsons Disease Diagnostic Markers with Gene Solutions, LLC

    Updated: 2009-12-23 00:04:24
    , . , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags cytogenetic analyses laboratory productivity neurodegenerative diseases neurological diseases reagents Transgenomic , Inc . Executes License Option agreement for Parkinsons Disease Diagnostic Markers with Gene Solutions , LLC Posted on 23 December 2009 12:04 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary But often the disease has progressed significantly before a diagnosis can be accurately made and treatment initiated . Damaged or mutated mitochondrial DNA mtDNA leads to cellular metabolism disorders by interfering with energy production . A large body of research conducted over the past twenty years has implicated mitochondrial abnormalities in certain neurodegenerative diseases including Parkinsons disease . In addition , we see potential application for COLD-PCR , a technology licensed exclusively from the Dana Farber Cancer Institute for applications to mitochondrial DNA mutation enrichment and detection . About Gene SolutionsGene Solutions , LLC is an early-stage discovery and development company based in focused on genetic

  • Boston University reseachers develop faster, cheaper DNA sequencing method

    Updated: 2009-12-22 21:01:12
    Story Summary: edu617-353-9766A team of researchers led by Boston University biomedical engineer Amit Meller is using electrical fields to efficiently draw long strands of DNA through nanopore sensors, drastically reducing the number. (BOSTON) EMBARGOED UNTIL 1 P. M. EST 12/20/09 — Boston University biomedical engineers have devised a method for making future genome sequencing [...] Related posts:Faster, Cheaper DNA Sequencing Method Developed By Boston University ReseachersKey Advance In DNA Sequencing With NanoporesKey Advance In DNA Sequencing With Nanopores

  • Transplant guide highlights daily infection risks from factors like pets and food

    Updated: 2009-12-22 15:44:11
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags face masks michaels tobacco smoke viral infections water rides Transplant guide highlights daily infection risks from factors like pets and food Posted on 22 December 2009 15:44 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Avoiding infection should be an important part of everyday life . Reduce the risk of respiratory infections by avoiding crowded places like shopping malls when their immune system is suppressed . Avoid smoking and exposure to tobacco smoke , which can raise the risk of bacterial and viral infections , and marijuana use , because of its association with fungal spores . Prevent waterborne infections by only drinking water from safe sources and avoid inadvertent water ingestion during activities such as swimming , diving , boating , using a hot tub or going on water rides at amusement parks . Animal feces are also dangerous , so cleaning out cages and litter boxes should be avoided or disposable gloves and face masks worn . Practice safe sex by using latex condoms with casual partners . Patients should be aware that

  • Researchers discover new ways to treat chronic infections

    Updated: 2009-12-22 14:06:11
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags antibiotic resistance biofilms chronic infections genetic program immune system Researchers discover new ways to treat chronic infections Posted on 22 December 2009 14:06 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary We have found a pathway of how the formation of biofilms is controlled , Sauer said . Petrova documented a previously unknown genetic program composed of several regulators by looking for changes in phosphorylation patterns in Pseudomonas aeruginosa . These regulators cannot only be used to stop the development of biofilms at various stages in their growth but also to revert established biofilms to an earlier developmental stage . The problem you have when you have a chronic infection is that your immune system is trying to clear the infection but is unable to , Sauer said . Sauers research is driven by several key questions , she said : Can we outsmart the biofilms In addition to regulators required for biofilm formation , Sauer and her team recently identified a regulator that is only expressed in biofilms and which seems

  • Stem Cell Dangers Expected To Decrease

    Updated: 2009-12-22 06:39:11
    Dr. Shinya Yamanaka, a scientist who did key scientific experiments to turn adult cells into pluripotent stem cells is the subject of a New York Times story on the bright prospects for stem cell research. Yamanaka sees both embryonic and induced pluripotent stem cells as still risky for therapies. But he's optimistic about solving these problems. As for the cells with which he now works, iPS cells, many hurdles remain before they are truly as versatile as the embryonic stem cells they mimic. “Embryonic stem cells are not safe,” he said. “But at the moment, iPS cells are more dangerous.” For instance, many skin cells only partly complete the transition to stem cells, and there are no reliable markers yet...

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